Car auction week in Scottsdale/Phoenix in January, Grand National Roadster Show Pomona in January, Hot August Nights Reno in August.
It also depends on what your interests are in. For 1962-1972 (roughly) Muscle Cars, Corvettes, and a few surprises, it's hard to top MCACN.
A large Goodguys event, like Columbus (I've been told) is also worth attending.
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